Summary: Electroactive microbes is the driving force for the bioelectrochemical degradation of organic pollutants, but the underlying microbial interactions between electrogenesis and pollutant degradation have not been clearly identified.Here, we combined stable isotope-assisted metabolomics (SIAM) and 13C-DNA stable isotope probing (DNA-SIP) to i
The insulin receptor (IR) presents by alternative splicing two isoforms: IRA and IRB.The differential physiological and pathological role of both isoforms is not completely known, and it is determinant the different binding affinity for insulin-like growth factor.IRB is more abundant in adult tissues and it exerts mainly the metabolic actions of in
Abstract Modelling Crank And Shroud insulin-glucose homeostasis may provide novel functional insights.In particular, simple models are clinically useful if they yield diagnostic methods.Examples include the homeostasis model assessment (HOMA) and the quantitative insulin sensitivity check index (QUICKI).However, limitations of these approaches have
The ventricles of the brain remain perhaps the largest anatomic structure in the human body without established primary purpose, even though their existence has been known at least since described by Aristotle.We hypothesize that the ventricles help match a stroke volume of arterial blood that arrives into the rigid cranium with an equivalent volum
Abstract Background Inhibitors of the protease calpain are known to have selectively toxic effects on Yohimbe Plasmodium falciparum.The enzyme has a natural inhibitor calpastatin and in eukaryotes is responsible for turnover of proteins containing short sequences enriched in certain amino acids (PEST sequences).The genome of P.falciparum was search